Not sure if there's anything special about this USB 3.0 card but this is the one I tested on:
http://goo.gl/UBafhUAnd this is the one I'm waiting on because I need 5 ports:
http://goo.gl/nXOB8h---------------------------
I would advise to remove all USB2 connector leads off the Motherboard and disable in Bios...dedicate 1 USB3 card to Midi and another USB3 card to anything else.
If you use Windows, download 'USBDeview' and hot plug USB2 devices in and out..you can observe the piles of entries created by USB2 live (loads of obsolete ones also)
** If you have more than one of the same model USB Midi Interface (not sure about different models) then try this procedure:
1/ Disable all USB2 sockets physically and Bios
2/ Insert USB3 cards (dedicate one to USB Interfaces)
3/ Boot and use USBDeveiw (as Admin) to delete ALL entries (you will need to run a PS2 mouse (best) or a wireless mouse (and re-insert after all devices are deleted - but NOT into the card reserved for Midi)
4/ Insert ONE of the identical Midi Interfaces into every port consecutively of the USB3 card dedicated to Midi (you will see entries for each USB port with it's driver via USBDeview **sort by Driver Filename)
5/ Insert all identical Midi Interfaces into this one USB3 card and leave them there
6/ Connect a Midi Controller into one of the Midi Interfaces on Midi Port 1
7/ Use Midi-Ox and go to Options | Midi Devices and highlight ONLY Port1 for each Midi Interface on both input and output sides. Save this setup as 'USB3 Test' (or whatever)
8/ Go to View | Port Status and NOTE which input 'Port 1' is lit up when playing the controller...this will serve as a reference point during multiple cold shutdowns (we want that to stay the same always)
9/ Go to View | Port Routings and clear ALL connections.
10/ Connect the
Input Port of the Midi Controller (by dragging patch lead) to Output Port 1 of every other of your identical Midi Interfaces
11/ Go back to View | Port Status and NOTE the names of the other hubs lighting up on Port 1 on the Outputs in MidiOx and on the actual Interface. Identical USB Hubs will display with a numbered prefix, except #1 and will be reflected in CopperLan Manager also.
12/ After confirming connection between all Interfaces and taking notes of their names, do a shutdown and very importantly: Remove the Power cord and wait 30 seconds before re-plugging/ Re-booting.
13/ Go to View | Port Status and play the controller...is everything the same? If yes, then do step 12 again...still good?
14/ Go into CopperLan Manager and make connections identical to the setup in Midiox | View | Port Routings
15/ Shutdown MidiOx and play the controller...if port 1 on the other Interfaces light up, congratulations...your at the stage I'm at (fingers crossed) with this multiple/identical USB Midi Hub problem, whereby all the devices get renamed at start-up, rendering any routing unworkable.
16/ If you dare, then proceed with full CopperLan Manager routings and TAKE snapshots along the way
I'll report back on how my 5 port USB PCI-e card / 5 x Motu Midi128 interfaces goes down.
Cheers